Targeted Gene Bisulfite Sequencing Identifies Differential Methylation in p21
Ramya T. Kolli, Travis C. Glenn, Bradley T. Brown, Lillie Marie A. Barnett, Lawrence Harold Lash, Brian S. Cummings
The paper develops TGBS, a targeted bisulfite sequencing method, to analyze methylation changes in p21 across human and rat cells, showing differential methylation and response to 5-Aza treatment.
bioRxiv · Apr 6, 2018 · PreprintMolecular Biology