General prediction of T cell receptor antigen specificity from sequence using AlphaFold 3
Lawson Woods, Brandon Neff, Kamel Lahouel, Antoine Goursaud, Mete Mulazimoglu, Kameron Bates, Cristian Tomasetti, John A. Altin
This paper uses AlphaFold 3 to predict T cell receptor antigen specificity from sequence, achieving high accuracy on unseen epitopes.
Science Advances · Oct 30, 2026Peer-reviewedImmunology