Towards Identifying a Molecular Activator of Spreading Depolarization Generated by the Ischemic Brain
Chloe A. Lowry, Julia A. Hellas, Nikita Ollen‐Bittle, Peter J. Gagolewicz, Brian M. Bennett, R. David Andrew
This study identifies a compound released by ischemic brain tissue that promotes spreading depolarization and shows it synergizes with NKA inhibition to cause RBC hemolysis.
bioRxiv · Apr 30, 2026 · PreprintNeuroscience