Structural basis for the access and binding of resolvin D1 (RvD1) to formyl peptide receptor 2 (FPR2/ALX), a class A GPCR
Brian Mun, Peter Obi, Christopher T. Szlenk, Senthil Natesan
This study investigates how RvD1 accesses and binds to FPR2/ALXR using molecular dynamics and metadynamics simulations, revealing structural insights and potential therapeutic implications.
bioRxiv · Sep 23, 2024 · PreprintBiophysics