Author

Brian S. Helfer

MIT Lincoln Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 4

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:variant calling· 3 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Assay:GWAS summary statistics· 1 Organism:human· 1

Frequent Co-Authors

Darrell O. RickeiD· 4 shared Albert ReutheriD· 1 shared Jeremy KepneriD· 1 shared Philip Fremont‐SmithiD· 1 shared Siddharth SamsiiD· 1 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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4 shared papersBioinformatics

Darrell O. RickeORCID

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4 papers

Recent·Most cited

The Genetic Chain Rule for Probabilistic Kinship Estimation

Brian S. Helfer, Philip Fremont‐Smith, Darrell O. Ricke

This paper introduces a method for kinship estimation using large SNP panels, resolving parent-sibling relationships and distinguishing degrees of kinship.

bioRxiv · Apr 25, 2019 · PreprintBioinformatics

SNP Identity Searching Across Ethnicities, Kinship, and Admixture

Brian S. Helfer, Darrell O. Ricke

The paper presents models for SNP-based identification and mixture analysis across ethnicities, kinship, and admixture using in silico datasets.

bioRxiv · Mar 12, 2019 · PreprintBioinformatics

11 Million SNP Reference Profiles for Identity Searching Across Ethnicities, Kinship, and Admixture

Brian S. Helfer, Darrell O. Ricke

The paper creates a reference dataset of 11 million SNP profiles for DNA forensics applications across diverse ethnicities, kinship, and admixture.

bioRxiv · May 15, 2018 · PreprintBioinformatics

A Linear Algebra Approach to Fast DNA Mixture Analysis Using GPUs

Siddharth Samsi, Brian S. Helfer, Jeremy Kepner, Albert Reuther, Darrell O. Ricke

The paper presents a GPU-accelerated DNA mixture analysis method using linear algebra, enabling fast comparison of DNA samples by leveraging matrix multiplication.

IEEE High Performance Extreme Computing Conference · Sep 1, 2017Peer-reviewedBioinformatics