Unusually Rapid Isomerization of Aspartic Acid in Tau
Thomas A. Shoff, Brielle L. Van Orman, Vivian C. Onwudiwe, Joseph C. Genereux, Ryan R. Julian
The paper measures Asp isomerization rates in proteins, finding that tau isomerizes faster than other proteins, possibly linked to Alzheimer's disease cognition.
ACS Chemical Neuroscience · Jan 30, 2025Peer-reviewedBiochemistry