Estrogen receptor regulates hormone-induced growth arrest in a luminal A like breast cancer model
Lacey Haddon, Sunny Hu, Hosna Jabbari, Brittney Loney, Zelda-Saidman Lichtensztejn, Richard Fahlman, Mary Hitt, Kirk McManus, Kelly Dabbs, John Mackey, Judith Hugh
This study develops a luminal A-like breast cancer model by increasing ER expression in MCF-7 cells and shows it promotes anti-proliferative responses to estrogen through cell cycle regulation and chromatin changes.
bioRxiv · Apr 23, 2018 · PreprintPathology