Author

Bryan Le

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:eQTL / molecular QTL mapping· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adrian Gonzalez· 1 shared Alec Leonetti· 1 shared Arslan A. ZaidiiD· 1 shared Aya S. KlosiD· 1 shared D N Taylor· 1 shared Eva E. StüekeniD· 1 shared Joanne Sarah BodeniD· 1 shared Juntao Zhong· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Adrian Gonzalez

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Beyond copy number: The regulatory architecture of mitochondrial DNA gene expression

Parisa Riahi, Sharwary Raghupathy, Bryan Le, Sol Taylor-Brill, D N Taylor, Rajiv C. McCoy, Shweta Ramdas, Arslan A. Zaidi

The paper investigates the relationship between mtDNA copy number and gene expression, finding they are largely decoupled and that mtDNA accessibility, not copy number, better explains expression variation.

bioRxiv · May 30, 2026 · PreprintGenomics

Time-resolved phylogenomics analysis reveals patterns in biosphere nutrient limitation through Earth history

Zhanghan Ni, Troy Osborn, Juntao Zhong, Adrian Gonzalez, Will Puzella, Aya S. Klos, Bryan Le, Alec Leonetti, Joanne Sarah Boden, Eva E. Stüeken, Rika E. Anderson

This study uses phylogenomic analysis to trace the timing of nutrient limitation genes across Earth's history, showing phosphorus genes emerged early, nitrogen later, and iron-related siderophores possibly as early as the Archean.

bioRxiv · Nov 13, 2025 · PreprintBioinformatics