Neuropathology of RAN translation proteins in Fragile X-associated Tremor/Ataxia Syndrome
Amy Krans, Geena Skariah, Yuan Zhang, Bryana Bayly, Peter K. Todd
The paper investigates RAN translation products in FXTAS brains, finding FMRpolyG accumulates in ubiquitin and p62-positive inclusions, while FMRpolyA is less abundant and less frequently co-localized.
Acta Neuropathologica Communications · Oct 30, 2019Peer-reviewedNeuroscience