Identification of determinants of differential chromatin accessibility through a massively parallel genome-integrated reporter assay
Jennifer Hammelman, Konstantin Krismer, Budhaditya Banerjee, David Kenneth Gifford, Richard I. Sherwood
The paper introduces MIAA, a method to measure DNA accessibility changes caused by synthetic oligonucleotide motifs, and identifies key transcription factor motifs influencing chromatin accessibility in stem cells and endoderm.
Genome Research · Oct 1, 2020Peer-reviewedGenomics