In Vitro Generation and Characterization of The Wu Syndrome Model That Causes Mental Retardation in Neural Cell Lines
Sumeyye Seher Karaman, Tuba Sevik, Selin Akdemir, Burak Bilgin, Esra Karadeli, Dilay Yalcin, Buse Baran, Beste Gelsin, Buket Budaklar, Berranur Sert, Gamze Gülden, Cihan Taştan
This study creates an in vitro model of Wu Syndrome using genetic modification in neural cell lines to characterize new GRIA3 variants and their functional effects.
bioRxiv · Jul 1, 2024 · PreprintMolecular Biology