Genetic context drives evolution of divergent antibiotic survival phenotypes in Staphylococcus epidermidis
Carolin Martina Kobras, Carlota Losa Mediavilla, James C. Littlefair, Elizabeth Cummins, C J Woolley, Seungwon Ko, Priyanshu Singh Raikwar, Keith A. Jolley, Samuel Keir Sheppard, Mathew Stracy
This study shows that antibiotic resistance and tolerance in Staphylococcus epidermidis are genetically linked but phenotypically distinct, shaped by complex epistatic interactions.
bioRxiv · May 30, 2026 · PreprintMicrobiology