The structure of the monobactam-producing thioesterase domain of SulM forms a unique complex with the upstream carrier protein domain
K. D. Patel, R. A. Oliver, M. S. Lichstrahl, R. Li, C. A. Townsend, A. M. Gulick
The paper determines the structure of the thioesterase domain of SulM and its complex with the upstream carrier protein domain, revealing a constrained active site for β-lactam formation.
bioRxiv · Apr 6, 2024Biochemistry