How asbestos drives the tissue towards tumors: YAP activation, macrophage and mesothelial precursor recruitment, RNA editing and somatic mutations
H. Rehrauer, L. Wu, W. Blum, L. Pecze, T. Henzi, V. Serre-Beinier, C. Aquino, B. Vrugt, M. de Perrot, B. Schwaller, E. Felley-Bosco
This study shows asbestos exposure triggers YAP/TAZ activation, macrophage recruitment, and RNA editing in mesothelium before tumor development.
bioRxiv · Aug 31, 2017Cancer Biology