Author

C. Baldwin

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Physiology· 1

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Approach:experimental assay· 1 Organism:mouse· 1

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J. L. Estall· 1 shared J. Marcinkiewicz· 1 shared K. Bouyakdan· 1 shared N. Jouvet· 1 shared T. Alquier· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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1 shared paperPhysiology

J. L. Estall

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1 paper

Recent·Most cited

Expression of a tetracycline-controlled transactivator (Tet-On/Off system) in beta cells reduces insulin expression and secretion in mice

N. Jouvet, K. Bouyakdan, C. Baldwin, J. Marcinkiewicz, T. Alquier, J. L. Estall

This study shows that expressing tetracycline-controlled transactivators in beta cells reduces insulin expression and secretion in mice, highlighting concerns about their use in genome editing.

bioRxiv · Feb 10, 2021Physiology