Structural basis for catalysis and substrate specificity of human ACAT1
H. Qian, X. Zhao, R. Yan, S. Gao, X. Sun, C. C. L. Wong, N. Yan
The paper presents the cryo-EM structure of human ACAT1 and reveals its catalytic mechanism and substrate preference for unsaturated acyl chains.
bioRxiv · Jan 6, 2020Biochemistry