E4F1 and ZNF148 are transcriptional activators of the A57C and wildtype TERT promoter
B. H. Chua, L. Ferry, C. Domrane, N. Zaal Anuar, A. Wittek, S. Jha, F. Butter, D. G. Tenen, P.-A. Defossez, D. Kappei
The paper identifies E4F1 and ZNF148 as transcriptional activators of the A57C and wildtype TERT promoter, respectively, and shows their role in upregulating TERT transcription and telomerase activity.
bioRxiv · Jan 13, 2023Cancer Biology