The mRNACalc web server accounts for the hypochromicity of modified nucleosides and enables the accurate quantification of nucleoside-modified mRNA.
E. Finol, S. E. Krul, S. J. Hoehn, C. E. Crespo-Hernandez
The paper develops mRNACalc, a web server that corrects for UV absorbance underestimation in nucleoside-modified mRNAs, improving quantification accuracy.
bioRxiv · Jul 27, 2023 · PreprintBiochemistry