Force-dependent facilitated dissociation can generate protein-DNA catch bonds
K. Dahlke, J. Zhao, C. E. Sing, E. J. Banigan
The paper develops a model showing that protein-DNA bonds can become catch bonds through facilitated dissociation, where competitor proteins enhance dissociation but forces suppress it by inhibiting competitor binding.
bioRxiv · Jul 9, 2019Biophysics