BioengineeringbioRxiv
Epigenetic control of multiple genes with a single lentiviral vector encoding transcriptional repressors fused to compact zinc finger arrays
D. Monteferrario, M. David, S. K. Tadi…·D. Fenard
This paper develops a lentiviral system to simultaneously repress multiple genes using zinc finger repressors, showing efficient and long-term gene silencing without DNA editing.
DOI 10.1016/j.omtm.2024.101255