Role of RNA Guanine Quadruplexes in Favoring the Dimerization of SARS Unique Domain in Coronaviruses
C. Hognon, T. Miclot, C. Garcia Iriepa, A. France-Monerris, S. Grandemange, A. Terenzi, M. Marazzi, G. Barone, A. Monari
This study investigates how RNA guanine quadruplexes interact with the SARS Unique Domain using molecular dynamics simulations to understand their role in viral infection and potential therapeutic targeting.
bioRxiv · Apr 7, 2020Biophysics