Author

C. Hognon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 7 Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 5 Approach:statistical model· 5 Research Focus:chromatin & epigenetic regulation· 4 Assay:DNA methylation· 4 Approach:deep learning· 3 Approach:mechanistic / dynamical model· 3 Approach:biophysical modeling· 2 Approach:experimental assay· 2

Frequent Co-Authors

A. MONARI· 9 shared G. Barone· 5 shared T. Miclot· 5 shared A. Terenzi· 4 shared E. Bignon· 4 shared S. Grandemange· 4 shared M. Marazzi· 2 shared A. France-Monerris· 1 shared

Activity by Year

2020-2023 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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9 shared papersBiophysics

A. MONARI

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Author profile →

10 papers

Recent·Most cited

The dynamics of protein-RNA interfaces using all-atom molecular dynamics simulations

A. Sabei, C. Hognon, J. Martin, E. Frezza

This study uses all-atom molecular dynamics simulations to analyze the dynamics of protein-RNA interfaces, revealing structural rearrangements and alternative residue-residue contacts.

bioRxiv · Nov 7, 2023Biochemistry

Never cared for what they do. High structural stability of Guanine-quadruplexes in presence of strand-break damages

T. Miclot, C. Hognon, E. Bignon, A. Terenzi, S. Grandemange, G. Barone, A. MONARI

The paper shows that guanine-quadruplexes remain structurally stable even with two strand breaks, unlike B-DNA, suggesting an evolutionary mechanism to mitigate ionizing radiation damage.

bioRxiv · Dec 1, 2021Biophysics

Structural and functional characterization of DdrC, a novel DNA damage-induced nucleoid associated protein involved in DNA compaction

A.-S. Banneville, C. Bouthier de la Tour, C. Hognon, J.-P. Colletier, J.-M. Teulon, A. Le Roy, J.-L. Pellequer, A. Monari, F. Dehez, F. Confalonieri, P. Servant, J. Timmins

This study characterizes DdrC, a DNA damage-induced protein in D. radiodurans, showing it compacts DNA and modulates its topology to aid in DNA repair.

bioRxiv · Oct 27, 2021Microbiology

The iron maiden. Cytosolic aconitase/IRP1 conformational transition in the regulation of ferritin translation and iron hemostasis

C. Hognon, E. Bignon, G. Harle, N. Touche, S. Grandemange, A. Monari

This study uses molecular dynamics simulations to analyze how the iron-sulfur cluster influences the conformational transition of aconitase/IRP1 and its interaction with mRNA, impacting ferritin translation and iron homeostasis.

bioRxiv · Jul 28, 2021Biophysics

How fragile we are. Influence of STimulator of INterferon Genes, STING, variants on pathogen recognition and immune response efficiency

J. Morere, C. Hognon, T. Miclot, T. Jiang, E. Dumont, G. Barone, E. Bignon, A. MONARI

The paper uses molecular simulations and machine learning to analyze STING variants and explains how structural changes affect immune response efficiency.

bioRxiv · Jul 12, 2021Biochemistry

Staring at the naked Goddess. Unraveling structure and reactivity of Artemis endonuclease interacting with a DNA double strand.

C. Hognon, A. MONARI

This study uses molecular dynamics simulations to investigate Artemis endonuclease's interaction with DNA and its catalytic mechanism.

bioRxiv · Jun 2, 2021Biophysics

Structure and dynamics of RNA guanine quadruplexes in SARS-CoV-2 genome. Original strategies against emerging viruses

T. Miclot, C. Hognon, E. Bignon, A. Terenzi, M. Marazzi, G. Barone, A. MONARI

The paper calculates the first G4 structure of the RG-1 RNA sequence in SARS-CoV-2 genome using multiscale modeling and validates it with circular dichroism spectra, showing its stability and potential interaction with inhibitory ligands.

bioRxiv · May 20, 2021Biophysics

Forever Young: Structural Stability of Telomeric Guanine-Quadruplexes in Presence of Oxidative DNA Lesions.

T. Miclot, C. Corbier, A. Terenzi, C. Hognon, S. Grandemange, G. Barone, A. MONARI

The paper investigates the structural stability of telomeric G-quadruplexes in the presence of oxidative DNA lesions using experimental and computational methods.

bioRxiv · Nov 26, 2020Biophysics

Photoinduced DNA Lesions in Dormant Bacteria. The Peculiar Route Leading to Spore Photoproduct Unraveled by Multiscale Molecular Dynamics

A. Frances-Monerris, C. Hognon, T. Douki, A. MONARI

This paper uses molecular dynamics simulations to explain why spores form spore photoproducts instead of cyclobutane pyrimidine dimers under UV radiation.

bioRxiv · Apr 28, 2020Biophysics

Role of RNA Guanine Quadruplexes in Favoring the Dimerization of SARS Unique Domain in Coronaviruses

C. Hognon, T. Miclot, C. Garcia Iriepa, A. France-Monerris, S. Grandemange, A. Terenzi, M. Marazzi, G. Barone, A. Monari

This study investigates how RNA guanine quadruplexes interact with the SARS Unique Domain using molecular dynamics simulations to understand their role in viral infection and potential therapeutic targeting.

bioRxiv · Apr 7, 2020Biophysics