Systematic review and meta-analysis of protocols and yield of direct from sputum sequencing of Mycobacterium tuberculosis
Brendon C. Mann, Johannes Loubser, Shatha Omar, C. Glanz, Y. Ektefaie, Karen Rita Jacobson, R.M. Warren, Maha R Farhat
This study identifies factors affecting the success of direct sputum whole genome sequencing for Mycobacterium tuberculosis, highlighting optimal pre-processing steps and the negative impact of sodium hydroxide decontamination.
Tuberculosis · Jan 29, 2026Peer-reviewedMicrobiology