Loss of Dna2 nuclease activity results in decreased Exo1-mediated resection at DNA double strand breaks.
A. Mojumdar, C. Granger, M. Lunke, J. Cobb
This study shows that loss of Dna2 nuclease activity reduces Exo1-mediated resection at DNA double strand breaks, leading to increased NHEJ and decreased HR.
bioRxiv · Oct 25, 2023 · PreprintBiochemistry