Author

C. K. Lumby

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 3 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

C. J. R. Illingworth· 3 shared D. Weissman· 1 shared J. Breuer· 1 shared L. Zhao· 1 shared M. Ghafari· 1 shared N. R. Nene· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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3 shared papersEvolutionary Biology

C. J. R. Illingworth

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3 papers

Recent·Most cited

A large effective population size for within-host influenza virus infection

C. K. Lumby, L. Zhao, J. Breuer, C. J. R. Illingworth

The paper estimates the effective population size of influenza virus within-host infections, finding it large enough that genetic drift has minimal impact, with positive selection limited by infection duration.

bioRxiv · Apr 17, 2020Evolutionary Biology

Inferring transmission bottleneck size from viral sequence data using a novel haplotype reconstruction method

M. Ghafari, C. K. Lumby, D. Weissman, C. J. R. Illingworth

This paper introduces a novel haplotype reconstruction method to infer viral transmission bottleneck size from sequence data, finding that most influenza A transmission events involve 1-13 viral particles.

bioRxiv · Jan 3, 2020Evolutionary Biology

A novel framework for inferring parameters of transmission from viral sequence data

C. K. Lumby, N. R. Nene, C. J. R. Illingworth

This paper introduces a framework for inferring viral transmission parameters from sequence data, showing that 2-6 viruses typically initiate infection and demonstrating the impact of selection on transmission inferences.

bioRxiv · Apr 18, 2018Evolutionary Biology