Cholesterol modulates the human FPN1 iron export function in plasma membrane liquid-ordered microdomains
R. Debbiche, C. Ka, I. Gourlaouen, S. Maestri, K. Uguen, P.-A. Jaffres, I. Callebaut, G. Le Gac
This study shows cholesterol modulates FPN1 iron export function by affecting its localization in plasma membrane microdomains and sensitivity to hepcidin.
bioRxiv · Dec 14, 2023 · PreprintBiochemistry