Disease progression modelling reveals heterogeneity in trajectories of Lewy-type alpha-synuclein pathology
S. E. Mastenbroek, J. W. Vogel, L. E. Collij, G. E. Serrano, C. Tremblay, A. L. Young, R. A. Arce, H. A. Shill, E. D. Driver-Dunckley, S. H. Mehta, C. M. Belden, A. Atri, P. Choudhury, F. Barkhof, C. H. Adler, , O. Hansson
The paper models disease progression in Lewy body disorders using neuropathological data, identifying three distinct trajectories of alpha-synuclein pathology with different clinical associations.
bioRxiv · Dec 5, 2023Pathology