An anti-CRISPR protein induces strong non-specific DNA binding activity in a CRISPR-Cas complex
W.-T. Lu, C. N. Trost, H. Muller-Esparza, L. Randau, A. R. Davidson
This study shows that AcrIF9 enhances non-specific DNA binding in a CRISPR-Cas complex, which is conserved across homologues and suggests a new mechanism for Acr function.
bioRxiv · May 28, 2020 · PreprintMicrobiology