Characterisation of deubiquitylating enzymes in the cellular response to high-LET ionising radiation and complex DNA damage
R. Carter, C. Nickson, J. Thompson, A. Kacperek, M. Hill, J. L. Parsons
This study identifies USP6 as a key regulator of cell survival after high-LET radiation by stabilizing PARP-1, essential for repairing complex DNA damage.
bioRxiv · Oct 25, 2018Cancer Biology