Author

C. Nyhoegen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

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Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2

Frequent Co-Authors

H. Uecker· 2 shared S. Bonhoeffer· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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2 shared papersEvolutionary Biology

H. Uecker

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2 papers

Recent·Most cited

The many dimensions of combination therapy: How to combine antibiotics to limit resistance evolution

C. Nyhoegen, S. Bonhoeffer, H. Uecker

This study evaluates combination antibiotic therapy to limit resistance evolution by analyzing drug interactions and optimal dosing strategies using a stochastic pharmacodynamic model.

bioRxiv · Nov 29, 2023Evolutionary Biology

Sequential antibiotic therapy in the lab and in the patient

C. Nyhoegen, H. Uecker

This study compares antibiotic cycling strategies in lab and patient models, finding that rapid cycling is effective in the lab but slower cycling may be better in patients due to pharmacokinetic factors and drug interactions.

bioRxiv · Jun 17, 2022 · PreprintEvolutionary Biology