Role of coiled-coil registry shifts in activation of human Bicaudal D2 for dynein recruitment upon cargo-binding
C. R. Noell, J. Y. Loh, E. W. Debler, K. M. Loftus, H. Cui, B. B. Russ, P. Goyal, S. R. Solmaz
This paper investigates how coiled-coil registry shifts in BicD2 activate dynein recruitment upon cargo-binding, linking structural changes to disease mechanisms.
bioRxiv · May 15, 2019Biophysics