Author

J. Y. Loh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

H. Cui· 2 shared P. Goyal· 2 shared S. R. Solmaz· 2 shared B. B. Russ· 1 shared C. R. Noell· 1 shared E. W. Debler· 1 shared K. M. Loftus· 1 shared K. M. Trybus· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

H. Cui

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Author profile →

2 papers

Recent·Most cited

Coiled-coil registry shifts in the F684I mutant of Bicaudal result in cargo-independent activation of dynein motility

H. Cui, K. M. Trybus, M. Y. Ali, P. Goyal, K. Zhang, J. Y. Loh, S. R. Solmaz

The paper shows that a coiled-coil registry shift in the F684I mutant of BicD activates dynein motility without cargo, and suggests this mechanism may modulate cargo selection in BicD2.

bioRxiv · Nov 29, 2019Biophysics

Role of coiled-coil registry shifts in activation of human Bicaudal D2 for dynein recruitment upon cargo-binding

C. R. Noell, J. Y. Loh, E. W. Debler, K. M. Loftus, H. Cui, B. B. Russ, P. Goyal, S. R. Solmaz

This paper investigates how coiled-coil registry shifts in BicD2 activate dynein recruitment upon cargo-binding, linking structural changes to disease mechanisms.

bioRxiv · May 15, 2019Biophysics