c. ramseyer

Curvature increases permeability of the plasma membrane for ions, water and the anti-cancer drugs cisplatin and gemcitabine

This study shows that membrane curvature significantly increases permeability for ions, water, and anti-cancer drugs cisplatin and gemcitabine using molecular dynamics simulations.

Permeation of cisplatin through the membranes of normal and cancer cells: a molecular dynamics study

This study uses molecular dynamics to show that cancer cell membranes, with reduced lipid asymmetry and cholesterol, are less permeable to cisplatin than normal cell membranes.