Receptor binding and tissue architecture explain the morphogen local-to-global mobility transition
S. Zhu, Y. T. Loo, S. Veerapathiran, T. Y. J. Loo, B. N. Tran, C. Teh, J. Zhong, P. T. Matsudaira, T. E. Saunders, T. Wohland
The paper shows that tissue architecture and receptor binding can explain the transition from local to global morphogen diffusion, without needing additional regulatory mechanisms.
bioRxiv · Apr 28, 2024 · PreprintBiophysics