Eco-evolutionary dynamics of pathogen immune-escape: deriving a population-level phylodynamic curve
B. F. Nielsen, C. M. Saad-Roy, C. J. E. Metcalf, C. Viboud, B. T. Grenfell
The paper develops a stochastic framework to model how immunity influences viral adaptation rates, showing how parameters like immunity strength and transmissibility shape phylodynamic curves and escape variant emergence risks.
bioRxiv · Jul 23, 2024Ecology