Laplacian eigenmaps and principal curves for high resolution pseudotemporal ordering of single-cell RNA-seq profiles
Kieran Campbell, Chris P Ponting, Caleb Webber
This paper introduces a method combining laplacian eigenmaps and principal curves to improve pseudotemporal ordering of single-cell RNA-seq data by addressing noise robustness.
bioRxiv · Sep 18, 2015 · PreprintBioinformatics