Clonal interference and changing selective pressures shape the escape of SARS-CoV-2 from hundreds of antibodies
Hugh K. Haddox, Omar Abdel Aziz, Jared Galloway, Javen Kent, Cameron R Cooper, Chris Jennings-Shaffer, Will Dumm, Seth D Temple, Jesse D. Bloom, Frederick A. Matsen IV
This study examines how SARS-CoV-2 evolved to escape 1,603 antibodies by analyzing mutation dynamics and selective pressures over 3.5 years of the pandemic.
Virus Evolution · Jan 1, 2026Peer-reviewedMicrobiology