SpheroMap Cytometry: a novel spatial flow cytometry approach to evaluate immune response in PDAC spheroids
Sara E. Castro-Silva, Camila Bonaldo, Patrícia Vianna Bonini Palma, Pedro Luiz Porfírio Xavier, Raphael Lucas More, Maristela Delgado Orellana, Sâmia Rigotto Caruso, Rodrigo Alexandre Panepucci
This paper introduces SpheroMap Cytometry, a spatial flow cytometry method to analyze immune cell infiltration in PDAC spheroids, revealing hypoxia-driven changes in T-cell distribution and function.
bioRxiv · Aug 8, 2025 · PreprintCancer Biology