High-throughput 3D super-resolution imaging in deep tissue
Zhenhong Du, Jiajia Chen, Cancan Gao, Jiayu Li, Qin Ru, Yao Zheng, Wei Gong, Ke Si
This paper introduces 3D-FUDIP, a method that improves spatial resolution in fluorescence imaging by decoupling deblurring and denoising, achieving 8-fold resolution improvement and 6-fold SNR increase with reduced photon usage.
bioRxiv · Mar 7, 2025 · PreprintNeuroscience