NeurosciencebioRxivPreprint
High-throughput 3D super-resolution imaging in deep tissue
Zhenhong Du, Jiajia Chen, Cancan Gao…·Ke Si
This paper introduces 3D-FUDIP, a method that improves spatial resolution in fluorescence imaging by decoupling deblurring and denoising, achieving 8-fold resolution improvement and 6-fold SNR increase with reduced photon usage.
DOI 10.1101/2025.03.07.641978