CASK hypomorph mice display cone photoreceptor dysfunction
Sheida Hashemi, Sara Y. Sabbagh, Khushi Talajia, James A. Fortenberry, Saba Tufail, Candice Turner, Konark Mukherjee
This study shows that Cask knock-in mice exhibit cone photoreceptor dysfunction, reduced visual acuity, and lowered cone-specific opsin levels, linking CASK LOF to retinopathy.
bioRxiv · Jan 16, 2026 · PreprintNeuroscience