A novel eukaryotic RdRP-dependent small RNA pathway represses antiviral immunity by controlling an ERK pathway component in the black-legged tick
Canran Feng, Kyosuke Torimaru, Mandy Yu Theng Lim, Li-Ling Chak, Masami Shiimori, Kosuke Tsuji, Tetsuya Tanaka, Junko Iida, Katsutomo Okamura
The paper identifies RdRP-dependent sRNA pathways in ticks that regulate immune response by controlling an ERK pathway component, revealing a novel mechanism of antiviral immunity suppression.
PLoS ONE · Mar 30, 2023Peer-reviewedMolecular Biology