NeuroscienceNeurobiology of AgingPeer-reviewed
Reduced serotonin receptors and transporters in normal aging adults: a meta-analysis of PET and SPECT imaging studies
Teresa M. Karrer, Casey L. McLaughlin, Carmela P. Guaglianone, Gregory Russell Samanez-Larkin
This study meta-analyzes PET and SPECT imaging data to show age-related reductions in serotonin receptors and transporters, with larger declines in 5-HT-2A receptors compared to 5-HT-1A.