Reference-free deconvolution of DNA methylation data and mediation by cell composition effects
Eugene Andres Houseman, Molly L Kile, David C Christiani, Tan A Ince, Karl T Kelsey, Carmen J Marsit
The paper introduces a reference-free method to deconvolve DNA methylation data, estimating cell type proportions and evaluating their biological relevance using 23 Infinium datasets.
bioRxiv · Jan 23, 2016Bioinformatics