BioinformaticsbioRxiv
Reference-free deconvolution of DNA methylation data and mediation by cell composition effects
Eugene Andres Houseman, Molly L Kile, David C Christiani…·Carmen J Marsit
The paper introduces a reference-free method to deconvolve DNA methylation data, estimating cell type proportions and evaluating their biological relevance using 23 Infinium datasets.
DOI 10.1186/s12859-016-1140-4