Author

Carol Smith

New York State Department of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Organism:E. coli· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Joseph T. WadeiD· 2 shared Claire RioualeniD· 1 shared Devon M. FitzgeraldiD· 1 shared Gabriele BaniulyteiD· 1 shared James E. GalaganiD· 1 shared Jonathan PlitnickiD· 1 shared Julio Collado‐VidesiD· 1 shared Laura Gómez-RomeroiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioinformatics

Joseph T. WadeORCID

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2 papers

Recent·Most cited

Predictive Biophysical Neural Network Modeling of a Compendium of in vivo Transcription Factor DNA Binding Profiles for Escherichia coli

Patrick Lally, Laura Gómez-Romero, Víctor H. Tierrafría, Patricia Aquino, Claire Rioualen, Xiaoman Zhang, Sunyoung Kim, Gabriele Baniulyte, Jonathan Plitnick, Carol Smith, Mohan Babu, Julio Collado‐Vides, Joseph T. Wade, James E. Galagan

The paper maps DNA binding of 139 E. coli TFs using ChIP-Seq and trains BoltzNet, a neural network that predicts TF binding energy from DNA sequence, validated with biophysical experiments.

Nature Communications · May 7, 2025Peer-reviewedBioinformatics

The evolutionary impact of Intragenic FliA Promoters in Proteobacteria

Devon M. Fitzgerald, Carol Smith, Pascal Lapierre, Joseph T. Wade

The paper investigates intragenic FliA promoters in E. coli, showing most are active but not conserved, with one exception that constrains gene evolution.

Molecular Microbiology · Feb 24, 2018Peer-reviewedGenetics