Gabriele Baniulyte

This study shows that GR activation reorganizes Wnt/LEF1 regulatory circuitry in B-ALL, influencing therapeutic response and resistance through chromatin state changes and gene regulation.

The paper maps DNA binding of 139 E. coli TFs using ChIP-Seq and trains BoltzNet, a neural network that predicts TF binding energy from DNA sequence, validated with biophysical experiments.

The paper identifies a bacterial uORF, toiL, that responds to multiple classes of ribosome-targeting antibiotics by altering RNA secondary structure and regulating gene expression.

The paper introduces p53motifDB, a database integrating genomic data and p53 binding motifs to help generate hypotheses about p53 activity in the human genome.

The paper investigates how DNA sequence and cellular context influence p63-mediated transcription through MPRA in various contexts, finding that p63RE-bound elements show varied activity linked to GC content and p53 binding.

This study identifies shared gene targets regulated by p53 and ATF4, revealing convergent mechanisms in metabolic and pro-apoptotic gene control.