Computer-guided design of Z domain peptides with improved inhibition of VEGF
Carsten Geist, Abibe Useini, Aleksandr Kazimir, Richy Kümpfel, Jens Meiler, Christina Lamers, Stefan Kalkhof, Georg Kuenze
This study designs improved VEGFA inhibitors using computational tools, achieving higher affinity than existing peptides with minimal experimental rounds.
bioRxiv · Nov 29, 2024 · PreprintBiochemistry