Effect of ligands on stability of H-Ras GTPase
Elizaveta A Kovrigina, Casey O’Connor, Evgenii L Kovrigin
This study investigates how calcium and magnesium ions affect the stability of Ras in different nucleotide-bound states, showing significant contributions from an allosteric ion-binding site in GDP-bound Ras.
bioRxiv · Aug 21, 2017 · PreprintBiochemistry