OXA-181 transmission confounded by a stable IncX3 plasmid
Tricia S E Lee, Liam Nguyen, Brian M. Forde, Toby I Maidment, Suifang Ye, Andrew Henderson, Elliott Geoffrey Playford, Naomi J Runnegar, Belinda Henderson, Catherin Watson, Margaret Lindsay, Evan Bursle, Joel Douglas, Jocelyn Hume, David L. Paterson, , Leah Wendy Roberts
This study analyzes the spread of blaOXA-181-producing bacteria in Australia, finding that the IncX3 plasmid is highly stable with minimal genetic variation, suggesting that genomic similarity does not necessarily indicate recent transmission.
medRxiv · Aug 26, 2026 · PreprintGenetic & Genomic Medicine